Bioanalytical Assessment of Plasma Concentrations of Angiotensin-Converting Enzyme II Inhibitors and Angiotensin Receptor Blockers: A Pilot Study Among Patients Hospitalized with Acute Heart Failure.
Assessment of patient medication adherence, medical record accuracy, and medication blood concentrations for prescription and over-the-counter medications.
Adherence Assessment Via Comprehensive Identification and Quantitation of Circulating Medications with Significant Correlation to Lower Blood Pressure Observed in Hypertensive Patients.
Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring.
Co-prescription trends in a large cohort of subjects predict substantial drug-drug interactions.
Valproic Acid-Induced Changes of 4D Nuclear Morphology in Astrocyte Cells.
Ketamine’s pharmacogenomic network in human brain contains sub-networks associated with glutamate neurotransmission and with neuroplasticity.
Early single-dose treatment with exosomes provides neuroprotection and improves blood-brain barrier integrity in swine model of traumatic brain injury and hemorrhagic shock.
Druggable transcriptional networks in the human neurogenic epigenome: Transcription factors and chromatin remodeling complexes reveal novel drug-disease pathways.
Parental allele-specific genome architecture and transcription during the cell cycle
Robust Segmentation of Lung in Chest X-Ray: Applications in Analysis of Acute Respiratory Distress Syndrome.
3D shape modeling for cell nuclear morphological analysis and classification.
A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer’s disease.
Deep learning in pharmacogenomics: from gene regulation to patient stratification.
Genome architecture mediates transcriptional control of human myogenic reprogramming.
Improvement of blood-brain barrier integrity in traumatic brain injury and hemorrhagic shock following treatment with valproic acid and fresh frozen plasma.
Pharmacogenomics in the Age of GWAS, Omics Atlases, and PheWAS.
Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.
The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.
Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.
Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.
Network reconstruction reveals that valproic acid activates neurogenic transcriptional programs in adult brain following traumatic injury.
Alterations in the human proteome following administration of valproic acid.
Stress and Glucocorticoid Receptor Transcriptional Programming in Time and Space: Implications for the Brain-Gut Axis.
Linking MedDRA-Coded Clinical Phenotypes to Biological Mechanisms by The Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors.
A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis.
Emerging DNA Sequencing Technologies and Applications, In Next Generation Sequencing Informatics, Second Edition.
Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.
The epigenome, 4D Nucleome and next-generation neuropsychiatric pharmacogenomics.
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