Publications

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Bioanalytical Assessment of Plasma Concentrations of Angiotensin-Converting Enzyme II Inhibitors and Angiotensin Receptor Blockers: A Pilot Study Among Patients Hospitalized with Acute Heart Failure.

American Journal of Therapeutics
2019 Nov 10

Jama Network | Open
Assessment of patient medication adherence, medical record accuracy, and medication blood concentrations for prescription and over-the-counter medications.

JAMA Network Open
2018 Nov 2

Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study.

Journal of the American Geriatrics Society
2019 Nov

Adherence Assessment Via Comprehensive Identification and Quantitation of Circulating Medications with Significant Correlation to Lower Blood Pressure Observed in Hypertensive Patients.

Hypertension
2018

Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring.

PLOS One
2017 Sept 28

Co-prescription trends in a large cohort of subjects predict substantial drug-drug interactions.

PLOS One
2015 Mar 4

ACS Chemical Neuroscience
Managing psychotropic medications in complex, real-world patients using comprehensive therapeutic Drug Monitoring.

ASC Chemical Neuroscience
2017

Medication exposure in highly adherent psychiatry patients.

ASC Chemical Neuroscience
2017 Nov 20

Valproic Acid-Induced Changes of 4D Nuclear Morphology in Astrocyte Cells.

Submitted to bioRxiv and Nature Communications
2020 June

Ketamine’s pharmacogenomic network in human brain contains sub-networks associated with glutamate neurotransmission and with neuroplasticity.

Submitted to bioRxiv
2020 April

Early single-dose treatment with exosomes provides neuroprotection and improves blood-brain barrier integrity in swine model of traumatic brain injury and hemorrhagic shock.

Journal of Trauma and Acute Care Surgery
2020

Druggable transcriptional networks in the human neurogenic epigenome: Transcription factors and chromatin remodeling complexes reveal novel drug-disease pathways.

Pharmacological Reviews
2019

Parental allele-specific genome architecture and transcription during the cell cycle

Cell, in press
2019

Robust Segmentation of Lung in Chest X-Ray: Applications in Analysis of Acute Respiratory Distress Syndrome.

Radiology: Artificial Intelligence ScholarOne
2019

3D shape modeling for cell nuclear morphological analysis and classification. 

Scientific Reports
2018

A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer’s disease. 

GigaScience
2018

Deep learning in pharmacogenomics: from gene regulation to patient stratification.

Pharmacogenomics
2018

Genome architecture mediates transcriptional control of human myogenic reprogramming.

iScience
2018

Improvement of blood-brain barrier integrity in traumatic brain injury and hemorrhagic shock following treatment with valproic acid and fresh frozen plasma.

Critical Care Medicine
2018

Pharmacogenomics in the Age of GWAS, Omics Atlases, and PheWAS. 

arXiv preprint
2018

Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.

Journal of Surgical Research
2018

The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.

Pharmacogenomics
2018

Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.

Journal of Trauma and Acute Care Surgery
2018

Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.

Methods
2017

Network reconstruction reveals that valproic acid activates neurogenic transcriptional programs in adult brain following traumatic injury.

Pharmaceutical Research
2017

Alterations in the human proteome following administration of valproic acid. 

Journal of Trauma and Acute Care Surgery
2016

Stress and Glucocorticoid Receptor Transcriptional Programming in Time and Space: Implications for the Brain-Gut Axis.

Neurogastroenterology and Motility
2016 Jan 28

Linking MedDRA-Coded Clinical Phenotypes to Biological Mechanisms by The Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors.

Journal of Drug Safety
2016 Mar 22

A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis.

Pharmacogenomics
2015

Emerging DNA Sequencing Technologies and Applications, In Next Generation Sequencing Informatics, Second Edition.

Oxford University Press.
2015

Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.

Pharmacogenomics
2015

The epigenome, 4D Nucleome and next-generation neuropsychiatric pharmacogenomics.

Pharmacogenomics
2015

Valproic acid induces prosurvival transcriptomic changes in swine subjected to traumatic injury and hemorrhagic shock.

Journal of Trauma and Acute Care Surgery Oxford
2018

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