Publications that support medication-response intelligence.
Source-linked research across medication exposure, adherence, pharmacogenomics, AI, biomedical informatics, and translational omics.
Featured medication-response evidence.
Featured records emphasize Phenomics Health, Precera Bioscience, and the Sano Informed Prescribing evidence lineage across medication exposure, adherence, blood concentration monitoring, and drug-interaction risk.
Bioanalytical Assessment of Plasma Concentrations of Angiotensin-Converting Enzyme II Inhibitors and Angiotensin Receptor Blockers: A Pilot Study Among Patients Hospitalized with Acute Heart Failure.
Legacy featured Sano/Precera-lineage medication-exposure study using blood concentration assessment in hospitalized acute heart-failure patients.
Open source recordAssessment of patient medication adherence, medical record accuracy, and medication blood concentrations for prescription and over-the-counter medications.
Sano/Precera-lineage study focused on measured medication exposure, adherence, and medical-record accuracy.
Open source recordSupratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study.
Legacy featured medication-exposure study connecting measured psychotropic drug levels with delirium duration.
Open source recordAdherence Assessment Via Comprehensive Identification and Quantitation of Circulating Medications with Significant Correlation to Lower Blood Pressure Observed in Hypertensive Patients.
Legacy featured study linking comprehensive circulating medication assessment with blood-pressure outcomes in hypertensive patients.
Open source recordMedication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring.
PLOS source lists Sano Laboratories / Sano Informed Prescribing affiliations and support.
Open source recordCo-prescription trends in a large cohort of subjects predict substantial drug-drug interactions.
PLOS source lists Sano Informed Prescribing affiliation and funding support.
Open source recordSelective serotonin/serotonin-norepinephrine reuptake inhibitor serum concentrations' association with delirium duration.
PubMed source lists Precera Bioscience, Inc. in grants and funding.
Open source recordFull evidence library with article-level links.
Browse the supporting publication set across medication exposure, AI, pharmacogenomics, informatics, and translational biology. Each row links to the article, PubMed or PMC record, DOI, publisher page, preprint, or source PDF.
Bioanalytical Assessment of Plasma Concentrations of Angiotensin-Converting Enzyme II Inhibitors and Angiotensin Receptor Blockers: A Pilot Study Among Patients Hospitalized with Acute Heart Failure.
American Journal of Therapeutics · 2019 Nov 10
Assessment of patient medication adherence, medical record accuracy, and medication blood concentrations for prescription and over-the-counter medications.
JAMA Network Open · 2018 Nov 2
Supratherapeutic Psychotropic Drug Levels in the Emergency Department and Their Association with Delirium Duration: A Preliminary Study.
Journal of the American Geriatrics Society · 2019 Nov
Adherence Assessment Via Comprehensive Identification and Quantitation of Circulating Medications with Significant Correlation to Lower Blood Pressure Observed in Hypertensive Patients.
Hypertension · 2018
Medication adherence, medical record accuracy, and medication exposure in real-world patients using comprehensive medication monitoring.
PLOS One · 2017 Sept 28
Co-prescription trends in a large cohort of subjects predict substantial drug-drug interactions.
PLOS One · 2015 Mar 4
Managing psychotropic medications in complex, real-world patients using comprehensive therapeutic Drug Monitoring.
ACS Chemical Neuroscience · 2017
Medication exposure in highly adherent psychiatry patients.
ACS Chemical Neuroscience · 2017 Nov 20
Valproic Acid-Induced Changes of 4D Nuclear Morphology in Astrocyte Cells.
Submitted to bioRxiv and Nature Communications · 2020 June
Ketamine’s pharmacogenomic network in human brain contains sub-networks associated with glutamate neurotransmission and with neuroplasticity.
Submitted to bioRxiv · 2020 April
Early single-dose treatment with exosomes provides neuroprotection and improves blood-brain barrier integrity in swine model of traumatic brain injury and hemorrhagic shock.
Journal of Trauma and Acute Care Surgery · 2020
Druggable transcriptional networks in the human neurogenic epigenome: Transcription factors and chromatin remodeling complexes reveal novel drug-disease pathways.
Pharmacological Reviews · 2019
Parental allele-specific genome architecture and transcription during the cell cycle
Cell, in press · 2019
Robust Segmentation of Lung in Chest X-Ray: Applications in Analysis of Acute Respiratory Distress Syndrome.
Radiology: Artificial Intelligence ScholarOne · 2019
3D shape modeling for cell nuclear morphological analysis and classification.
Scientific Reports · 2018
A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer’s disease.
GigaScience · 2018
Deep learning in pharmacogenomics: from gene regulation to patient stratification.
Pharmacogenomics · 2018
Genome architecture mediates transcriptional control of human myogenic reprogramming.
iScience · 2018
Improvement of blood-brain barrier integrity in traumatic brain injury and hemorrhagic shock following treatment with valproic acid and fresh frozen plasma.
Critical Care Medicine · 2018
Pharmacogenomics in the Age of GWAS, Omics Atlases, and PheWAS.
arXiv preprint · 2018
Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.
Journal of Surgical Research · 2018
The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.
Pharmacogenomics · 2018
Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.
Journal of Trauma and Acute Care Surgery · 2018
Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.
Methods · 2017
Network reconstruction reveals that valproic acid activates neurogenic transcriptional programs in adult brain following traumatic injury.
Pharmaceutical Research · 2017
Alterations in the human proteome following administration of valproic acid.
Journal of Trauma and Acute Care Surgery · 2016
Stress and Glucocorticoid Receptor Transcriptional Programming in Time and Space: Implications for the Brain-Gut Axis.
Neurogastroenterology and Motility · 2016 Jan 28
Linking MedDRA-Coded Clinical Phenotypes to Biological Mechanisms by The Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors.
Journal of Drug Safety · 2016 Mar 22
A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis.
Pharmacogenomics · 2015
Emerging DNA Sequencing Technologies and Applications, In Next Generation Sequencing Informatics, Second Edition.
Oxford University Press. · 2015
Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.
Pharmacogenomics · 2015
The epigenome, 4D Nucleome and next-generation neuropsychiatric pharmacogenomics.
Pharmacogenomics · 2015
Valproic acid induces prosurvival transcriptomic changes in swine subjected to traumatic injury and hemorrhagic shock.
Journal of Trauma and Acute Care Surgery Oxford · 2018
Metab2MeSH: annotating compounds with medical subject headings.
Bioinformatics · 2012
Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks.
Bioinformatics · 2010
Integrated metabolome and transcriptome analysis of the NCI60 dataset.
BMC Bioinformatics · 2011
ConceptGen: a gene set enrichment and gene set relation mapping tool.
Bioinformatics · 2010
Michigan molecular interactions r2: from interacting proteins to pathways.
Nucleic Acids Research · 2009
Integrating and annotating the interactome using the MiMI plugin for Cytoscape.
Bioinformatics · 2009
Epigenomics and the Brain-gut Axis: Impact of Adverse Childhood Experiences and Therapeutic Challenges.
Journal of Translational Gastroenterology · 2024 Jun
3D Cell Nuclear Morphology: Microscopy Imaging Dataset and Voxel-Based Morphometry Classification Results.
CVPR Workshops · 2018
Evaluation of Methods for Cell Nuclear Structure Analysis from Microscopy Data.
AIST Supplementary Proceedings · 2018
Hypothesis: Caco-2 cell rotational 3D mechanogenomic Turing patterns have clinical implications to colon crypts.
PMC source record · source-linked
Selective serotonin/serotonin-norepinephrine reuptake inhibitor serum concentrations’ association with delirium duration.
Journal of the American Geriatrics Society · 2024 Nov
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